Intratumoral genetic heterogeneity in metastatic melanoma is accompanied by variation in malignant behaviors

BACKGROUND: Intratumoral heterogeneity is a major obstacle for the treatment of cancer, as the presence of even minor populations that are insensitive to therapy can lead to disease relapse. Increased clonal diversity has been correlated with a poor prognosis for cancer patients, and we therefore ex...

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Detalles Bibliográficos
Autores principales: Anaka, Matthew, Hudson, Christopher, Lo, Pu-Han, Do, Hongdo, Caballero, Otavia L, Davis, Ian D, Dobrovic, Alexander, Cebon, Jonathan, Behren, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852494/
https://www.ncbi.nlm.nih.gov/pubmed/24119551
http://dx.doi.org/10.1186/1755-8794-6-40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852494/
https://www.ncbi.nlm.nih.gov/pubmed/24119551
http://dx.doi.org/10.1186/1755-8794-6-40

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