Trophic and proliferative effects of Shh on motor neurons in embryonic spinal cord culture from wildtype and G93A SOD1 mice

BACKGROUND: The developmental morphogen sonic hedgehog (Shh) may continue to play a trophic role in the support of terminally-differentiated motor neurons, of potential relevance to motor neuron disease. In addition, it may support the proliferation and differentiation of endogenous stem cells along...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoxing, Turnbull, Patrick, Peterson, Randy, Turnbull, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852546/
https://www.ncbi.nlm.nih.gov/pubmed/24119209
http://dx.doi.org/10.1186/1471-2202-14-119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852546/
https://www.ncbi.nlm.nih.gov/pubmed/24119209
http://dx.doi.org/10.1186/1471-2202-14-119

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