The 30-kDa and 38-kDa antigens from Mycobacterium tuberculosis induce partial maturation of human dendritic cells shifting CD4(+) T cell responses towards IL-4 production

BACKGROUND: Mycobacterium tuberculosis (Mtb) infections are still a major cause of death among all infectious diseases. Although 99% of individuals infected with Mtb develop a CD4(+) Th1 and CD8(+) T cell mediated immunity as measured by tuberculin skin test, this results only in partial protection...

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Detalles Bibliográficos
Autores principales: Heuer, Marion, Behlich, Anna-Sophie, Lee, Ji-Sook, Ribechini, Eliana, Jo, Eun-Kyeong, Lutz, Manfred B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852591/
https://www.ncbi.nlm.nih.gov/pubmed/24089996
http://dx.doi.org/10.1186/1471-2172-14-48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852591/
https://www.ncbi.nlm.nih.gov/pubmed/24089996
http://dx.doi.org/10.1186/1471-2172-14-48

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