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Embryonic stem cells shed new light on the developmental roles of p53

The viability and subtle developmental defects of p53 knockout mice suggest that p53 does not play major role in development. However, contradictory evidence also exists. This discrepancy mainly results from the lack of molecular and cellular mechanisms and the general fact that p53 activation requi...

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Detalles Bibliográficos
Autores principales: Shin, Min Hwa, He, Yunlong, Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852614/
https://www.ncbi.nlm.nih.gov/pubmed/24171803
http://dx.doi.org/10.1186/2045-3701-3-42