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PTPRO promoter methylation is predictive of poorer outcome for HER2-positive breast cancer: indication for personalized therapy

BACKGROUND: Protein Tyrosine Phosphatase Receptor-type O (PTPRO) has recently been in the spotlight as a tumor suppressor, whose encoding gene is frequently methylated in cancers. We examined the methylation status of the PTPRO gene promoter in breast cancer and evaluated the correlation between PTP...

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Detalles Bibliográficos
Autores principales: Huang, Yi-Teng, Li, Fei-Fei, Ke, Chen, Li, Zhou, Li, Zong-Tai, Zou, Xiao-Fang, Zheng, Xiao-Xuan, Chen, Yu-Ping, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852714/
https://www.ncbi.nlm.nih.gov/pubmed/24090193
http://dx.doi.org/10.1186/1479-5876-11-245