Decoy Oligonucleotide Rescues IGF1R Expression from MicroRNA-223 Suppression

A mature miRNA generally suppresses hundreds of mRNA targets. To evaluate the selective effect of synthetic oligonucleotide decoys on hsa-miR-223 activity, reporters containing 3’ untranslated regions (UTR) of IGF1R, FOXO1, POLR3G, FOXO3, CDC27, FBXW7 and PAXIP1 mRNAs were constructed for the lucife...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Li Hui, Cai, Qian Qian, Dong, Yi Wei, Wang, Rong, He, Bao Mei, Qi, Bing, Xu, Chang Jun, Wu, Xing Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852755/
https://www.ncbi.nlm.nih.gov/pubmed/24324762
http://dx.doi.org/10.1371/journal.pone.0082167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852755/
https://www.ncbi.nlm.nih.gov/pubmed/24324762
http://dx.doi.org/10.1371/journal.pone.0082167

Ejemplares similares