Cargando…

Decoy Oligonucleotide Rescues IGF1R Expression from MicroRNA-223 Suppression

A mature miRNA generally suppresses hundreds of mRNA targets. To evaluate the selective effect of synthetic oligonucleotide decoys on hsa-miR-223 activity, reporters containing 3’ untranslated regions (UTR) of IGF1R, FOXO1, POLR3G, FOXO3, CDC27, FBXW7 and PAXIP1 mRNAs were constructed for the lucife...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Li Hui, Cai, Qian Qian, Dong, Yi Wei, Wang, Rong, He, Bao Mei, Qi, Bing, Xu, Chang Jun, Wu, Xing Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852755/ https://www.ncbi.nlm.nih.gov/pubmed/24324762 http://dx.doi.org/10.1371/journal.pone.0082167

Ejemplares similares

MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R
por: Jia, Cheng You, et al.
Publicado: (2011)

Improved microRNA suppression by WPRE-linked tough decoy microRNA sponges
por: Hollensen, Anne Kruse, et al.
Publicado: (2017)

Down-Regulation of MicroRNA-223 Promotes Degranulation via the PI3K/Akt Pathway by Targeting IGF-1R in Mast Cells
por: Wang, Quan, et al.
Publicado: (2015)

Antineoplastic Effect of Decoy Oligonucleotide Derived from MGMT Enhancer
por: Canello, Tamar, et al.
Publicado: (2014)

Specific inhibition of splicing factor activity by decoy RNA oligonucleotides
por: Denichenko, Polina, et al.
Publicado: (2019)

MicroRNA-223-5p suppresses the progression of nasopharyngeal carcinoma by targeting DCLK1
por: Zhang, Zhixuan, et al.
Publicado: (2021)

High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries
por: Mullokandov, Gavriel, et al.
Publicado: (2012)

RNA accessibility impacts potency of Tough Decoy microRNA inhibitors
por: Hooykaas, Marjolein J. G., et al.
Publicado: (2018)

Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells
por: Haraguchi, Takeshi, et al.
Publicado: (2009)

MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue
por: Chuang, Tung-Yueh, et al.
Publicado: (2015)

Generation of MicroRNA-34 Sponges and Tough Decoys for the Heart: Developments and Challenges
por: Bernardo, Bianca C., et al.
Publicado: (2018)

MicroRNA-223 Suppresses IL-1β and TNF-α Production in Gouty Inflammation by Targeting the NLRP3 Inflammasome
por: Zhang, Quan-Bo, et al.
Publicado: (2021)

Interleukin-23 Mediates Osteoclastogenesis in Collagen-Induced Arthritis by Modulating MicroRNA-223
por: Chen, Shih-Yao, et al.
Publicado: (2022)

Role of MicroRNA-223 and MicroRNA-182 as Novel Biomarkers in Early Detection of Colorectal Cancer
por: Mahmoud, Hala A, et al.
Publicado: (2022)

MicroRNA-223 and microRNA-21 in peripheral blood B cells associated with progression of primary biliary cholangitis patients
por: Wang, Xiaomei, et al.
Publicado: (2017)

MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation
por: Zhou, Wenqing, et al.
Publicado: (2018)

MicroRNA-223 reversibly regulates erythroid and megakaryocytic differentiation of K562 cells
por: Yuan, Jin-Yun, et al.
Publicado: (2009)

MicroRNA-223 Regulates Granulopoiesis but Is Not Required for HSC Maintenance in Mice
por: Trissal, Maria C., et al.
Publicado: (2015)

MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal Pneumonia
por: Goekeri, Cengiz, et al.
Publicado: (2023)

An improved cucumber mosaic virus-based vector for efficient decoying of plant microRNAs
por: Liao, Qiansheng, et al.
Publicado: (2015)

Circular RNA circ-TNPO3 suppresses metastasis of GC by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL
por: Yu, Ting, et al.
Publicado: (2021)

Regulation of IGF -1 signaling by microRNAs
por: Jung, Hwa Jin, et al.
Publicado: (2015)

Inhibition of microRNA function by antimiR oligonucleotides
por: Stenvang, Jan, et al.
Publicado: (2012)

Highly efficient silencing of microRNA by heteroduplex oligonucleotides
por: Yoshioka, Kotaro, et al.
Publicado: (2019)

MicroRNA-223-3p is involved in fracture healing by regulating fibroblast growth factor receptor 2
por: Wang, Bin, et al.
Publicado: (2021)

Circulating MicroRNA223 is a New Biomarker for Inflammatory Bowel Disease
por: Wang, Huiling, et al.
Publicado: (2016)

MicroRNA-223 Regulates Retinal Function and Inflammation in the Healthy and Degenerating Retina
por: Fernando, Nilisha, et al.
Publicado: (2020)

Expression of microRNA-223 and microRNA-146b in serum and liver tissue of mice infected with Schistosoma mansoni
por: El-Taweel, Hend A, et al.
Publicado: (2022)

G4-DNA Formation in the HRAS Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy
por: Membrino, Alexandro, et al.
Publicado: (2011)

AAV-mediated expression of NFAT decoy oligonucleotides protects from cardiac hypertrophy and heart failure
por: Remes, Anca, et al.
Publicado: (2021)

Hsa_circ_0023642 promotes proliferation, invasion, and migration of gastric cancer by sponging microRNA‐223
por: Zhang, Yi, et al.
Publicado: (2020)

Inhibition of Tissue Factor Expression in Brain Microvascular Endothelial Cells by Nanoparticles Loading NF-κB Decoy Oligonucleotides
por: Wang, Huafang, et al.
Publicado: (2008)

MicroRNA-186 targets IGF-1R and exerts tumor-suppressing functions in glioma
por: Jiang, Jian, et al.
Publicado: (2022)

Decoy fitness peaks, tumor suppression, and aging
por: Higa, Kelly C., et al.
Publicado: (2019)

Oligonucleotides and microRNAs Targeting Telomerase Subunits in Cancer Therapy
por: Eckburg, Adam, et al.
Publicado: (2020)

Development of Antibody–Oligonucleotide Complexes for Targeting Exosomal MicroRNA
por: Yamayoshi, Asako, et al.
Publicado: (2020)

Lipid-modified G4-decoy oligonucleotide anchored to nanoparticles: delivery and bioactivity in pancreatic cancer cells
por: Cogoi, S., et al.
Publicado: (2016)

Paeonol Attenuated Inflammatory Response of Endothelial Cells via Stimulating Monocytes-Derived Exosomal MicroRNA-223
por: Liu, Yarong, et al.
Publicado: (2018)

Down-regulation of microRNA-320 suppresses cardiomyocyte apoptosis and protects against myocardial ischemia and reperfusion injury by targeting IGF-1
por: Song, Chun-Li, et al.
Publicado: (2016)

Bone Marrow–Derived MicroRNA‐223 Works as an Endocrine Genetic Signal in Vascular Endothelial Cells and Participates in Vascular Injury From Kawasaki Disease
por: Chu, Maoping, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_5p3rvrrpj62ipvtsbl5m041pp5