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Concordance between in vivo and postmortem measurements of cholinergic denervation in rats using PET with [(18)F]FEOBV and choline acetyltransferase immunochemistry

BACKGROUND: Fluorine-18 fluoroethoxybenzovesamicol ([(18)F]FEOBV) is a radioligand for the selective imaging of the vesicular acetylcholine transporter with positron emission tomography (PET). The current study demonstrates that pathological cortical cholinergic deafferentation can be quantified in...

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Detalles Bibliográficos
Autores principales: Parent, Maxime J, Cyr, Marilyn, Aliaga, Antonio, Kostikov, Alexey, Schirrmacher, Esther, Soucy, Jean-Paul, Mechawar, Naguib, Rosa-Neto, Pedro, Bedard, Marc-Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852759/
https://www.ncbi.nlm.nih.gov/pubmed/24103360
http://dx.doi.org/10.1186/2191-219X-3-70