Etoposide Induces Nuclear Re-Localisation of AID

During B cell activation, the DNA lesions that initiate somatic hypermutation and class switch recombination are introduced by activation-induced cytidine deaminase (AID). AID is a highly mutagenic protein that is maintained in the cytoplasm at steady state, however AID is shuttled across the nuclea...

Descripción completa

Detalles Bibliográficos
Autores principales: Lambert, Laurens J., Walker, Simon, Feltham, Jack, Lee, Heather J., Reik, Wolf, Houseley, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852760/
https://www.ncbi.nlm.nih.gov/pubmed/24324754
http://dx.doi.org/10.1371/journal.pone.0082110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852760/
https://www.ncbi.nlm.nih.gov/pubmed/24324754
http://dx.doi.org/10.1371/journal.pone.0082110

Ejemplares similares