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Added Value of HER-2 Amplification Testing by Multiplex Ligation-Dependent Probe Amplification in Invasive Breast Cancer

BACKGROUND: HER-2 is a prognostic and predictive marker, but as yet no technique is perfectly able to identify patients likely to benefit from HER-2 targeted therapies. We aimed to prospectively assess the added value of first-line co-testing by IHC, and multiplex ligation-dependent probe amplificat...

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Detalles Bibliográficos
Autores principales: Kuijpers, Chantal C. H. J., Moelans, Cathy B., van Slooten, Henk-Jan, Horstman, Anja, Hinrichs, John W. J., Al-Janabi, Shaimaa, van Diest, Paul J., Jiwa, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852761/
https://www.ncbi.nlm.nih.gov/pubmed/24324739
http://dx.doi.org/10.1371/journal.pone.0082018