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A systematic approach identifies FOXA1 as a key factor in the loss of epithelial traits during the epithelial-to-mesenchymal transition in lung cancer

BACKGROUND: The epithelial-to-mesenchymal transition is an important mechanism in cancer metastasis. Although transcription factors including SNAIL, SLUG, and TWIST1 regulate the epithelial-to-mesenchymal transition, other unknown transcription factors could also be involved. Identification of the f...

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Detalles Bibliográficos
Autores principales: Wang, Haiyun, Meyer, Clifford A, Fei, Teng, Wang, Gang, Zhang, Fan, Liu, X Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852829/
https://www.ncbi.nlm.nih.gov/pubmed/24093963
http://dx.doi.org/10.1186/1471-2164-14-680