Differential PKA activation and AKAP association determines cell fate in cancer cells

BACKGROUND: The dependence of malignant properties of colorectal cancer (CRC) cells on IGF1R signaling has been demonstrated and several IGF1R antagonists are currently in clinical trials. Recently, we identified a novel pathway in which cAMP independent PKA activation by TGFβ signaling resulted in...

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Detalles Bibliográficos
Autores principales: Hedrick, Erik D, Agarwal, Ekta, Leiphrakpam, Premila D, Haferbier, Katie L, Brattain, Michael G, Chowdhury, Sanjib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853032/
https://www.ncbi.nlm.nih.gov/pubmed/24083380
http://dx.doi.org/10.1186/1750-2187-8-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853032/
https://www.ncbi.nlm.nih.gov/pubmed/24083380
http://dx.doi.org/10.1186/1750-2187-8-10

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