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Incorporating substrate sequence motifs and spatial amino acid composition to identify kinase-specific phosphorylation sites on protein three-dimensional structures

BACKGROUND: Protein phosphorylation catalyzed by kinases plays crucial regulatory roles in cellular processes. Given the high-throughput mass spectrometry-based experiments, the desire to annotate the catalytic kinases for in vivo phosphorylation sites has motivated. Thus, a variety of computational...

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Detalles Bibliográficos
Autores principales: Su, Min-Gang, Lee, Tzong-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853090/
https://www.ncbi.nlm.nih.gov/pubmed/24564522
http://dx.doi.org/10.1186/1471-2105-14-S16-S2