Structure of yeast Argonaute with guide RNA

The RNA-induced silencing complex, comprising Argonaute and guide RNA, mediates RNA interference. Here we report the 3.2 Å crystal structure of Kluyveromyces Argonaute (KpAGO) fortuitously complexed with guide RNA originating from small-RNA duplexes autonomously loaded and processed by recombinant K...

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Detalles Bibliográficos
Autores principales: Nakanishi, Kotaro, Weinberg, David E., Bartel, David P., Patel, Dinshaw J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853139/
https://www.ncbi.nlm.nih.gov/pubmed/22722195
http://dx.doi.org/10.1038/nature11211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853139/
https://www.ncbi.nlm.nih.gov/pubmed/22722195
http://dx.doi.org/10.1038/nature11211

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