Chronic Increase of Urea Leads to Carbamylated Proteins Accumulation in Tissues in a Mouse Model of CKD

Carbamylation is a general process involved in protein molecular ageing due to the nonenzymatic binding of isocyanic acid, mainly generated by urea dissociation, to free amino groups. In vitro experiments and clinical studies have suggested the potential involvement of carbamylated proteins (CPs) in...

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Detalles Bibliográficos
Autores principales: Pietrement, Christine, Gorisse, Laëtitia, Jaisson, Stéphane, Gillery, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853192/
https://www.ncbi.nlm.nih.gov/pubmed/24324801
http://dx.doi.org/10.1371/journal.pone.0082506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853192/
https://www.ncbi.nlm.nih.gov/pubmed/24324801
http://dx.doi.org/10.1371/journal.pone.0082506

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