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L1 Cell Adhesion Molecule as a Potential Therapeutic Target in Murine Models of Endometriosis Using a Monoclonal Antibody Approach

BACKGROUND/AIMS: The neural cell adhesion molecule L1CAM is a transmembrane glycoprotein abnormally expressed in tumors and previously associated with cell proliferation, adhesion and invasion, as well as neurite outgrowth in endometriosis. Being an attractive target molecule for antibody-based ther...

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Detalles Bibliográficos
Autores principales: Silveira, Cássia G. T., Finas, Dominique, Hunold, Peter, Köster, Frank, Stroschein, Katharina, Canny, Geraldine O., Moldenhauer, Gerhard, Altevogt, Peter, Rody, Achim, Hornung, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853202/
https://www.ncbi.nlm.nih.gov/pubmed/24324802
http://dx.doi.org/10.1371/journal.pone.0082512