Saturable human neopterin response to interferon-α assessed by a pharmacokinetic-pharmacodynamic model

BACKGROUND: In this study, we developed a pharmacokinetic (PK)- pharmacodynamic (PD) model of a new sustained release formulation of interferon-α-2a (SR-IFN-α) using the blood concentration of IFN-α and neopterin in order to quantify the magnitude and saturation of neopterin production over time in...

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Detalles Bibliográficos
Autores principales: Jeon, Sangil, Juhn, Jae-Hyeon, Han, Seunghoon, Lee, Jongtae, Hong, Taegon, Paek, Jeongki, Yim, Dong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853247/
https://www.ncbi.nlm.nih.gov/pubmed/24088361
http://dx.doi.org/10.1186/1479-5876-11-240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853247/
https://www.ncbi.nlm.nih.gov/pubmed/24088361
http://dx.doi.org/10.1186/1479-5876-11-240

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