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Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy – Results of a United Kingdom phase II trial (CNS 2007 04)()

Diffuse intrinsic pontine glioma (DIPG) has a dismal prognosis with no chemotherapy regimen so far resulting in any significant improvement over standard radiotherapy. In this trial, a prolonged regimen (21/28 d) of temozolomide was studied with the aim of overcoming O(6)-methylguanine methyltransfe...

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Detalles Bibliográficos
Autores principales: Bailey, S., Howman, A., Wheatley, K., Wherton, D., Boota, N., Pizer, B., Fisher, D., Kearns, P., Picton, S., Saran, F., Gibson, M., Glaser, A., Connolly, D.J.A., Hargrave, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853623/
https://www.ncbi.nlm.nih.gov/pubmed/24011536
http://dx.doi.org/10.1016/j.ejca.2013.08.006