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Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy – Results of a United Kingdom phase II trial (CNS 2007 04)()
Diffuse intrinsic pontine glioma (DIPG) has a dismal prognosis with no chemotherapy regimen so far resulting in any significant improvement over standard radiotherapy. In this trial, a prolonged regimen (21/28 d) of temozolomide was studied with the aim of overcoming O(6)-methylguanine methyltransfe...
Autores principales: | Bailey, S., Howman, A., Wheatley, K., Wherton, D., Boota, N., Pizer, B., Fisher, D., Kearns, P., Picton, S., Saran, F., Gibson, M., Glaser, A., Connolly, D.J.A., Hargrave, D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853623/ https://www.ncbi.nlm.nih.gov/pubmed/24011536 http://dx.doi.org/10.1016/j.ejca.2013.08.006 |
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