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Molecular Docking Studies of Marine Diterpenes as Inhibitors of Wild-Type and Mutants HIV-1 Reverse Transcriptase

AIDS is a pandemic responsible for more than 35 million deaths. The emergence of resistant mutations due to drug use is the biggest cause of treatment failure. Marine organisms are sources of different molecules, some of which offer promising HIV-1 reverse transcriptase (RT) inhibitory activity, suc...

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Detalles Bibliográficos
Autores principales: Miceli, Leonardo A., Teixeira, Valéria L., Castro, Helena C., Rodrigues, Carlos R., Mello, Juliana F. R., Albuquerque, Magaly G., Cabral, Lucio M., de Brito, Monique A., de Souza, Alessandra M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853719/
https://www.ncbi.nlm.nih.gov/pubmed/24172210
http://dx.doi.org/10.3390/md11114127