Efficient Screening of Marine Extracts for Protease Inhibitors by Combining FRET Based Activity Assays and Surface Plasmon Resonance Spectroscopy Based Binding Assays

The screening of extracts from marine organisms is a widely used strategy to discover new drug leads. A common problem in the screening process is the generation of false positive hits through unspecific effects from the complex chemical composition of the crude extracts. In this study, we explored...

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Detalles Bibliográficos
Autores principales: Christopeit, Tony, Øverbø, Kersti, Danielson, U. Helena, Nilsen, Inge W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853728/
https://www.ncbi.nlm.nih.gov/pubmed/24177674
http://dx.doi.org/10.3390/md11114279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853728/
https://www.ncbi.nlm.nih.gov/pubmed/24177674
http://dx.doi.org/10.3390/md11114279

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