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O-6-methylguanine-deoxyribonucleic acid methyltransferase methylation enhances response to temozolomide treatment in esophageal cancer

BACKGROUND: World-wide, esophageal cancer is a growing epidemic and patients frequently present with advanced disease that is surgically inoperable. Hence, chemotherapy is the predominate treatment. Cytotoxic platinum compounds are mostly used, but their efficacy is only moderate. Newer alkylating a...

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Detalles Bibliográficos
Autores principales: Hasina, Rifat, Surati, Mosmi, Kawada, Ichiro, Arif, Qudsia, Carey, George B., Kanteti, Rajani, Husain, Aliya N., Ferguson, Mark K., Vokes, Everett E., Villaflor, Victoria M., Salgia, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853796/
https://www.ncbi.nlm.nih.gov/pubmed/24319345
http://dx.doi.org/10.4103/1477-3163.120632