Bactericidal activity of PA-824 against Mycobacterium tuberculosis under anaerobic conditions and computational analysis of its novel analogues against mutant Ddn receptor

BACKGROUND: The resurgence of multi-drug resistant tuberculosis (MDR-TB) and HIV associated tuberculosis (TB) are of serious global concern. To contain this situation, new anti-tuberculosis drugs and reduced treatment regimens are imperative. Recently, a nitroimidazole, PA-824, has been shown to be...

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Detalles Bibliográficos
Autores principales: Somasundaram, Sulochana, Anand, Ramaian Santhaseela, Venkatesan, Perumal, Paramasivan, Chinnambedu N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853930/
https://www.ncbi.nlm.nih.gov/pubmed/24083570
http://dx.doi.org/10.1186/1471-2180-13-218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853930/
https://www.ncbi.nlm.nih.gov/pubmed/24083570
http://dx.doi.org/10.1186/1471-2180-13-218

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