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Complexin-1 Enhances the On-Rate of Vesicle Docking via Simultaneous SNARE and Membrane Interactions

[Image: see text] In synaptic terminals, complexin is thought to have inhibitory and activating roles for spontaneous “mini” release and evoked synchronized neurotransmitter release, respectively. We used single vesicle–vesicle microscopy imaging to study the effect of complexin-1 on the on-rate of...

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Detalles Bibliográficos
Autores principales: Diao, Jiajie, Cipriano, Daniel J., Zhao, Minglei, Zhang, Yunxiang, Shah, Sachi, Padolina, Mark S., Pfuetzner, Richard A., Brunger, Axel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854000/
https://www.ncbi.nlm.nih.gov/pubmed/24083833
http://dx.doi.org/10.1021/ja407392n