Inherited common variants in mitochondrial DNA and invasive serous epithelial ovarian cancer risk

BACKGROUND: Mitochondria are the site of oxidative phosphorylation, a process which generates reactive oxygen species (ROS). Elevated ROS levels can lead to oxidative stress, a cellular state implicated in carcinogenesis. It is hypothesized that alternations in mitochondrial (MT) DNA, including heri...

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Detalles Bibliográficos
Autores principales: Earp, Madalene A, Brooks-Wilson, Angela, Cook, Linda, Le, Nhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854008/
https://www.ncbi.nlm.nih.gov/pubmed/24148579
http://dx.doi.org/10.1186/1756-0500-6-425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854008/
https://www.ncbi.nlm.nih.gov/pubmed/24148579
http://dx.doi.org/10.1186/1756-0500-6-425

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