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RNAi-mediated knockdown of pituitary tumor-transforming gene-1 (PTTG1) suppresses the proliferation and invasive potential of PC3 human prostate cancer cells

Pituitary tumor-transforming gene-1 (PTTG1) is a proto-oncogene that promotes tumorigenesis and metastasis in numerous cell types and is overexpressed in a variety of human tumors. We have demonstrated that PTTG1 expression was up-regulated in both human prostate cancer specimens and prostate cancer...

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Detalles Bibliográficos
Autores principales: Huang, S.Q., Liao, Q.J., Wang, X.W., Xin, D.Q., Chen, S.X., Wu, Q.J., Ye, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854157/
https://www.ncbi.nlm.nih.gov/pubmed/22872288
http://dx.doi.org/10.1590/S0100-879X2012007500126