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Silencing HIF-1α reduces the adhesion and secretion functions of acute leukemia hBMSCs

Hypoxia inducible factor-1α (HIF-1α) is an important transcription factor, which plays a critical role in the formation of solid tumor and its microenvironment. The objective of the present study was to evaluate the expression and function of HIF-1α in human leukemia bone marrow stromal cells (BMSCs...

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Detalles Bibliográficos
Autores principales: Zeng, Dong-Feng, Liu, Ting, Chang, Cheng, Zhang, Xi, Liang, Xue, Chen, Xing-Hua, Kong, Pei-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854177/
https://www.ncbi.nlm.nih.gov/pubmed/22948410
http://dx.doi.org/10.1590/S0100-879X2012007500107