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Silencing HIF-1α reduces the adhesion and secretion functions of acute leukemia hBMSCs
Hypoxia inducible factor-1α (HIF-1α) is an important transcription factor, which plays a critical role in the formation of solid tumor and its microenvironment. The objective of the present study was to evaluate the expression and function of HIF-1α in human leukemia bone marrow stromal cells (BMSCs...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Medicina Tropical
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854177/ https://www.ncbi.nlm.nih.gov/pubmed/22948410 http://dx.doi.org/10.1590/S0100-879X2012007500107 |