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Secretory TAT-peptide-mediated protein transduction of LIF receptor α-chain distal cytoplasmic motifs into human myeloid HL-60 cells

The distal cytoplasmic motifs of leukemia inhibitory factor receptor α-chain (LIFRα-CT3) can independently induce intracellular myeloid differentiation in acute myeloid leukemia (AML) cells by gene transfection; however, there are significant limitations in the potential clinical use of these motifs...

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Detalles Bibliográficos
Autores principales: Sun, Q., Xiong, J., Lu, J., Xu, S., Li, Y., Zhong, X.P., Gao, G.K., Liu, H.Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854185/
https://www.ncbi.nlm.nih.gov/pubmed/22714809
http://dx.doi.org/10.1590/S0100-879X2012007500101