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Pamidronate for the treatment of osteoporosis secondary to chronic cholestatic liver disease in Wistar rats

Osteoporosis is a major complication of chronic cholestatic liver disease (CCLD). We evaluated the efficacy of using disodium pamidronate (1.0 mg/kg body weight) for the prevention (Pr) or treatment (Tr) of cholestasis-induced osteoporosis in male Wistar rats: sham-operated (Sham = 12); bile duct-li...

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Detalles Bibliográficos
Autores principales: Pereira, F.A., Mattar, R., Facincani, I., Defino, H.L.A., Ramalho, L.N.Z., Jorgetti, V., Volpon, J.B., de Paula, F.J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854229/
https://www.ncbi.nlm.nih.gov/pubmed/22983176
http://dx.doi.org/10.1590/S0100-879X2012007500143