Heparan sulphate, its derivatives and analogues share structural characteristics that can be exploited, particularly in inhibiting microbial attachment

Heparan sulphate (HS) and the related polysaccharide, heparin, exhibit conformational and charge arrangement properties, which provide a degree of redundancy allowing several seemingly distinct sequences to exhibit the same activity. This can also be mimicked by other sulphated polysaccharides, both...

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Detalles Bibliográficos
Autores principales: Rudd, T.R., Hughes, A., Holman, J., de Oliveira Ferreira, E., Cavalcante Pilotto Domingues, R.M., Yates, E.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854285/
https://www.ncbi.nlm.nih.gov/pubmed/22473323
http://dx.doi.org/10.1590/S0100-879X2012007500048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854285/
https://www.ncbi.nlm.nih.gov/pubmed/22473323
http://dx.doi.org/10.1590/S0100-879X2012007500048

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