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Placental hydroxymethylation vs methylation at the imprinting control region 2 on chromosome 11p15.5

In addition to methylated cytosines (5-mCs), hydroxymethylcytosines (5-hmCs) are present in CpG dinucleotide-enriched regions and some transcription regulator binding sites. Unlike methylation, hydroxymethylation does not result in silencing of gene expression, and the most commonly used methods to...

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Detalles Bibliográficos
Autores principales: Magalhães, H.R., Leite, S.B.P., de Paz, C.C.P., Duarte, G., Ramos, E.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854339/
https://www.ncbi.nlm.nih.gov/pubmed/24270911
http://dx.doi.org/10.1590/1414-431X20133035