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TNNI3K is a novel mediator of myofilament function and phosphorylates cardiac troponin I

The phosphorylation of cardiac troponin I (cTnI) plays an important role in the contractile dysfunction associated with heart failure. Human cardiac troponin I-interacting kinase (TNNI3K) is a novel cardiac-specific functional kinase that can bind to cTnI in a yeast two-hybrid screen. The purpose of...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Wang, Lin, Song, Li, Zhang, Yan-Wan, Ye, Jue, Xu, Rui-Xia, Shi, Na, Meng, Xian-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854359/
https://www.ncbi.nlm.nih.gov/pubmed/23369981
http://dx.doi.org/10.1590/1414-431X20122515