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Chromogenic in situ hybridization compared with other approaches to evaluate HER2/neu status in breast carcinomas
Human epidermal growth factor receptor 2 (HER2) has been evaluated in breast cancer patients to identify those most likely to benefit from herceptin-targeted therapy. HER2 amplification, detected in 20-30% of invasive breast tumors, is associated with reduced survival and metastasis. The most freque...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854374/ https://www.ncbi.nlm.nih.gov/pubmed/23558859 http://dx.doi.org/10.1590/1414-431X20132483 |