BAFF promotes regulatory T-cell apoptosis and blocks cytokine production by activating B cells in primary biliary cirrhosis

Primary biliary cirrhosis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology. A number of questions regarding its etiology are unclear. CD4+CD25+ regulatory T cells (Tregs) play a critical role in self-tolerance and, for unknown reasons, their relative number...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Hu, Mintao, Zhang, Peng, Cao, Hong, Wang, Yongzhen, Wang, Zheng, Su, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2013
Materias:
Biomedical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854395/
https://www.ncbi.nlm.nih.gov/pubmed/23681290
http://dx.doi.org/10.1590/1414-431X20132665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854395/
https://www.ncbi.nlm.nih.gov/pubmed/23681290
http://dx.doi.org/10.1590/1414-431X20132665

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