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High plasma concentrations of asymmetric dimethylarginine inhibit ischemic cardioprotection in hypercholesterolemic rats

A low concentration of nitric oxide associated with a high concentration of asymmetric dimethylarginine (ADMA) can explain the lack of ischemic cardioprotection observed in the presence of hypercholesterolemia. The objective of the present study was to evaluate the effect of hypercholesterolemia on...

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Detalles Bibliográficos
Autores principales: Landim, M.B.P., Dourado, P.M.M., Casella-Filho, A., Chagas, A.C.P., da-Luz, P.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854396/
https://www.ncbi.nlm.nih.gov/pubmed/23681289
http://dx.doi.org/10.1590/1414-431X20132595