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The hydrogen sulfide donor, Lawesson's reagent, prevents alendronate-induced gastric damage in rats

Our objective was to investigate the protective effect of Lawesson's reagent, an H(2)S donor, against alendronate (ALD)-induced gastric damage in rats. Rats were pretreated with saline or Lawesson's reagent (3, 9, or 27 µmol/kg, po) once daily for 4 days. After 30 min, gastric damage was i...

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Detalles Bibliográficos
Autores principales: Nicolau, L.A.D., Silva, R.O., Damasceno, S.R.B., Carvalho, N.S., Costa, N.R.D., Aragão, K.S., Barbosa, A.L.R., Soares, P.M.G., Souza, M.H.L.P., Medeiros, J.V.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854416/
https://www.ncbi.nlm.nih.gov/pubmed/23969974
http://dx.doi.org/10.1590/1414-431X20133030