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Histone demethylase retinoblastoma binding protein 2 regulates the expression of α-smooth muscle actin and vimentin in cirrhotic livers

Liver cirrhosis is one of the most common diseases of Chinese patients. Herein, we report the high expression of a newly identified histone 3 lysine 4 demethylase, retinoblastoma binding protein 2 (RBP2), and its role in liver cirrhosis in humans. The siRNA knockdown of RBP2 expression in hepatic st...

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Detalles Bibliográficos
Autores principales: Wang, Q., Wang, L.X., Zeng, J.P., Liu, X.J., Liang, X.M., Zhou, Y.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854431/
https://www.ncbi.nlm.nih.gov/pubmed/24068189
http://dx.doi.org/10.1590/1414-431X20132843