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Target-directed catalytic metallodrugs

Most drugs function by binding reversibly to specific biological targets, and therapeutic effects generally require saturation of these targets. One means of decreasing required drug concentrations is incorporation of reactive metal centers that elicit irreversible modification of targets. A common...

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Detalles Bibliográficos
Autores principales: Joyner, J.C., Cowan, J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854446/
https://www.ncbi.nlm.nih.gov/pubmed/23828584
http://dx.doi.org/10.1590/1414-431X20133086