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A Sequential Vesicle Pool Model with a Single Release Sensor and a Ca(2+)-Dependent Priming Catalyst Effectively Explains Ca(2+)-Dependent Properties of Neurosecretion
Neurotransmitter release depends on the fusion of secretory vesicles with the plasma membrane and the release of their contents. The final fusion step displays higher-order Ca(2+) dependence, but also upstream steps depend on Ca(2+). After deletion of the Ca(2+) sensor for fast release – synaptotagm...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854459/ https://www.ncbi.nlm.nih.gov/pubmed/24339761 http://dx.doi.org/10.1371/journal.pcbi.1003362 |