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Determinants of Cell-to-Cell Variability in Protein Kinase Signaling
Cells reliably sense environmental changes despite internal and external fluctuations, but the mechanisms underlying robustness remain unclear. We analyzed how fluctuations in signaling protein concentrations give rise to cell-to-cell variability in protein kinase signaling using analytical theory a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854479/ https://www.ncbi.nlm.nih.gov/pubmed/24339758 http://dx.doi.org/10.1371/journal.pcbi.1003357 |