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Determinants of Cell-to-Cell Variability in Protein Kinase Signaling

Cells reliably sense environmental changes despite internal and external fluctuations, but the mechanisms underlying robustness remain unclear. We analyzed how fluctuations in signaling protein concentrations give rise to cell-to-cell variability in protein kinase signaling using analytical theory a...

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Detalles Bibliográficos
Autores principales:	Jeschke, Matthias, Baumgärtner, Stephan, Legewie, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854479/ https://www.ncbi.nlm.nih.gov/pubmed/24339758 http://dx.doi.org/10.1371/journal.pcbi.1003357

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