Defining the structural origin of the substrate sequence independence of O-GlcNAcase using a combination of molecular docking and dynamics simulation

Protein glycosylation with O-linked N-acetylglucosamine (O-GlcNAc) is a post-translational modification of serine/threonine residues in nucleocytoplasmic proteins. O-GlcNAc has been shown to play a role in many different cellular processes and O-GlcNAcylation is often found at sites that are also kn...

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Detalles Bibliográficos
Autores principales: Martin, Joanne C, Fadda, Elisa, Ito, Keigo, Woods, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854502/
https://www.ncbi.nlm.nih.gov/pubmed/24134879
http://dx.doi.org/10.1093/glycob/cwt094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854502/
https://www.ncbi.nlm.nih.gov/pubmed/24134879
http://dx.doi.org/10.1093/glycob/cwt094

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