Understanding Variation in Transcription Factor Binding by Modeling Transcription Factor Genome-Epigenome Interactions

Despite explosive growth in genomic datasets, the methods for studying epigenomic mechanisms of gene regulation remain primitive. Here we present a model-based approach to systematically analyze the epigenomic functions in modulating transcription factor-DNA binding. Based on the first principles of...

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Detalles Bibliográficos
Autores principales: Chen, Chieh-Chun, Xiao, Shu, Xie, Dan, Cao, Xiaoyi, Song, Chun-Xiao, Wang, Ting, He, Chuan, Zhong, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854512/
https://www.ncbi.nlm.nih.gov/pubmed/24339764
http://dx.doi.org/10.1371/journal.pcbi.1003367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854512/
https://www.ncbi.nlm.nih.gov/pubmed/24339764
http://dx.doi.org/10.1371/journal.pcbi.1003367

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