Desensitization properties of P2X3 receptors shaping pain signaling

ATP-gated P2X3 receptors are mostly expressed by nociceptive sensory neurons and participate in transduction of pain signals. P2X3 receptors show a combination of fast desensitization onset and slow recovery. Moreover, even low nanomolar agonist concentrations unable to evoke a response, can induce...

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Detalles Bibliográficos
Autores principales: Giniatullin, Rashid, Nistri, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854565/
https://www.ncbi.nlm.nih.gov/pubmed/24367291
http://dx.doi.org/10.3389/fncel.2013.00245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854565/
https://www.ncbi.nlm.nih.gov/pubmed/24367291
http://dx.doi.org/10.3389/fncel.2013.00245

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