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Minireview: Targeting GPCR Activated ERK Pathways for Drug Discovery

It has become clear in recent years that multiple signal transduction pathways are employed upon GPCR activation. One of the major cellular effectors activated by GPCRs is extracellular signal-regulated kinase (ERK). Both G-protein and β-arrestin mediated signaling pathways can lead to ERK activatio...

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Detalles Bibliográficos
Autores principales: Eishingdrelo, Haifeng, Kongsamut, Sathapana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854659/
https://www.ncbi.nlm.nih.gov/pubmed/24396730
http://dx.doi.org/10.2174/2213988501307010009