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Minireview: Targeting GPCR Activated ERK Pathways for Drug Discovery
It has become clear in recent years that multiple signal transduction pathways are employed upon GPCR activation. One of the major cellular effectors activated by GPCRs is extracellular signal-regulated kinase (ERK). Both G-protein and β-arrestin mediated signaling pathways can lead to ERK activatio...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854659/ https://www.ncbi.nlm.nih.gov/pubmed/24396730 http://dx.doi.org/10.2174/2213988501307010009 |