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A Multiplexed Fluorescent Calcium and NFAT Reporter Gene Assay to Identify GPCR Agonists
Intracellular calcium response and resulting calcium signaling to an agonist-GPCR interaction are important for the measurement of compound activity in the GPCR drug development. The increase in cytosol calcium concentration can be measured by the fluorescent calcium indicator dye such as Fluo-4 in...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bentham Open
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854663/ https://www.ncbi.nlm.nih.gov/pubmed/24396729 http://dx.doi.org/10.2174/2213988501307010001 |