A High Throughput Assay for Discovery of Small Molecules that Bind AMP-activated Protein Kinase (AMPK)

AMPK is a conserved heterotrimeric serine-threonine kinase that regulates anabolic and catabolic pathways in eukaryotes. Its central role in cellular and whole body metabolism makes AMPK a commonly proposed therapeutic target for illnesses characterized by abnormal energy regulation, including cance...

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Detalles Bibliográficos
Autores principales: Sinnett, Sarah E, Sexton, Jonathan Z, Brenman, Jay E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854666/
https://www.ncbi.nlm.nih.gov/pubmed/24396733
http://dx.doi.org/10.2174/2213988501307010030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854666/
https://www.ncbi.nlm.nih.gov/pubmed/24396733
http://dx.doi.org/10.2174/2213988501307010030

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