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Genome Wide Association Study (GWAS) of Chagas Cardiomyopathy in Trypanosoma cruzi Seropositive Subjects

BACKGROUND: Familial aggregation of Chagas cardiac disease in T. cruzi–infected persons suggests that human genetic variation may be an important determinant of disease progression. OBJECTIVE: To perform a GWAS using a well-characterized cohort to detect single nucleotide polymorphisms (SNPs) and ge...

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Detalles Bibliográficos
Autores principales: Deng, Xutao, Sabino, Ester C., Cunha-Neto, Edecio, Ribeiro, Antonio L., Ianni, Barbara, Mady, Charles, Busch, Michael P., Seielstad, Mark, Component, International
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854669/
https://www.ncbi.nlm.nih.gov/pubmed/24324551
http://dx.doi.org/10.1371/journal.pone.0079629