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Genome Wide Association Study (GWAS) of Chagas Cardiomyopathy in Trypanosoma cruzi Seropositive Subjects
BACKGROUND: Familial aggregation of Chagas cardiac disease in T. cruzi–infected persons suggests that human genetic variation may be an important determinant of disease progression. OBJECTIVE: To perform a GWAS using a well-characterized cohort to detect single nucleotide polymorphisms (SNPs) and ge...
Autores principales: | Deng, Xutao, Sabino, Ester C., Cunha-Neto, Edecio, Ribeiro, Antonio L., Ianni, Barbara, Mady, Charles, Busch, Michael P., Seielstad, Mark, Component, International |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854669/ https://www.ncbi.nlm.nih.gov/pubmed/24324551 http://dx.doi.org/10.1371/journal.pone.0079629 |
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